Research Theme

• Development and provision of small laboratory animal models for infectious disease research
• Generation of novel genetically engineered mice and development of innovative reproductive engineering technologies

Keyword

• Infectious disease model mice
• Type I interferon receptor (IFN-α/βR) knockout mice
• Severely immunodeficient NOG mice (NOD/Shi-scid, IL2RγKO)
• Reproductive and developmental engineering technologies

Overview of Research

• To collect and curate information on laboratory animals used in infectious disease research and to establish a comprehensive database of infectious disease animal models.
• Based on database analyses, we develop and provide versatile type I interferon receptor-deficient (IFN-α/βR KO), type II interferon receptor-deficient (IFN-γR KO), and aging mouse models with diverse genetic backgrounds to support a wide range of infectious disease research.