Research Theme

• Research and development of pandemic influenza vaccine
• Research and development of vaccines against COVID-19

Keyword

• vaccines
• influenza virus
• coronavirus

Overview of Research

• In order to manufacture a virus-inactivated whole-particle model vaccine using the current seasonal influenza vaccine-producing strain, a large-scale influenza virus culture method is examined.　We aim to establish a production method suitable for rapid vaccine production in the event of a pandemic by setting up a P3 laboratory equipped with a roller-type rotary culture device or a large-capacity bioreactor.
• Build a coronavirus vaccine evaluation system. Neutralization measurement methods using various corona mutant strains have already been established. Coronaviruses are constantly mutating, so we will establish a system to stably implement neutralization measurement methods using various cells and virus strains so that we can select an evaluation system suitable for new coronavirus vaccines.
• As a preparation for using an adjuvant, we will mainly construct a cell evaluation system by analyzing the adjuvant effect by measuring Th1/cytotoxic T cell activation.