Research Theme

• Development of vaccine platform using bacteria
• Vaccine development against viral infections

Keyword

• Vaccine platform
• Genetically modified bacteria
• SARS-CoV-2

Overview of Research

• We will develop a new genetically modified bacterial vaccine platform by combining the original technology successfully developed in our laboratory with the technology developed by our collaborators. This vaccine platform is safe for human use, has excellent adjuvant potential (immunogenicity), is highly capable of presenting antigens in both MHC class I and class II pathways, and induces long-lasting immunological memory. It is stable and can be stored at room temperature. By incorporating specific antigens, it can be used as a vaccine against infectious diseases such as specific viruses, but it also has a non-specific immunity-inducing ability, so it has a certain effect even against infectious diseases with mismatched antigens.
• Develop viral vaccines by incorporating antigens such as coronavirus into the vaccine platform.
• Create a pan-coronavirus vaccine to prepare for a possible third novel coronavirus epidemic in the future by using antigens that are widely conserved in coronaviruses as antigens.