Research Theme

• Comprehensive analysis of immune cells and tissue non-immune cells during respiratory infection and vaccination
• Establishment of pathogen detection technology with high sensitivity using quantum technology. 

Keyword

• Coronavirus
• Acquired immune system
• Respiratory infections such as influenza virus
• Diamond nanosensors
• AI nanopore

Overview of Research

• We will establish an analytical platform covering cellular, expression, and genetic analyses in immune cells and tissue non-immune cells during the development of respiratory infections such as coronaviruses and influenza viruses in clinical specimens, model animals, and at the time of vaccination.
• Using this analysis platform, identify immune cell fractions including novel cell fractions that are correlated with specific aggravation, sequelae, and vaccine efficacy at the onset of respiratory infections and vaccination, perform detailed analysis, identify diagnostic markers, and drug discovery targets.
• We will establish a diagnostic platform that can diagnose types of pathogens including mutations with ultra-high speed and ultra-high sensitivity using quantum technology such as AI nanopores and diamond nanosensors.
• In collaboration with the Department of Respiratory Medicine, Hokkaido University Hospital, we will build a system that collects and stores specimens from hospitalized patients with respiratory infections and those who have been vaccinated, and analyzes them on the above platform.