Research Theme

• Immunoprofiling of vaccinees
• Vaccine design based on profiling data
• Development of new vaccines with improved safety and effectiveness

Keyword

• Immunoprofiling
• Antibody
• Vaccine design
• New vaccine platform

Overview of Research

• We perform immunoprofiling of humoral, cellular, and innate immune responses that are elicited by vaccines. We monitor the durability and breadth of protective immunity against virus variants.
• We perform vaccine design by implementing structural biology and computational science approaches based on immunoprofiling data.The designed vaccines are aimed to elicit highly functional antibodies and immune cells that are poorly induced by the current vaccines.
• We develop less reactogenic vaccines by identifying the immunological pathways that are relevant to adverse events.