Development of flavivirus subviral particles with low cross-reactivity by mutations of a distinct antigenic domain

Nov 14, 2023

The research group of Professor Hirofumi Sawa, Dr.Tabata, and Dr.Itakura discovered the effectiveness of introducing mutations in the FL domain in MBFV SVPs with lineage I ISFV-derived amino acids to produce SVP antigens with low cross-reactivity and demonstrates an improvement in the accuracy of indirect ELISA-based serodiagnosis for MBFV infections. Please see the page below for details.